Midway via his vocation, Cees Dekker reinvented himself. Right after decades of hardcore physics, he shifted his emphasis to ‘nanobiology’ at the switch of the millennium. A phrase he coined himself, to be a make a difference of actuality.

Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules

Round the very same time, the group of Paul McEuen, who was then based for the University of California, Berkeley, confirmed related outcomes on ropes of bundled nanotubes. Depending on the wrapping angle, nanotubes can can be found in metallic or semiconducting variants, a prediction that we and Charles Lieber’s group at Harvard College independently confirmed working with scanning tunnelling spectroscopy experiments.

Deposition and atomic force microscopy of individual phthalocyanine polymers between nanofabricated electrodes

Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart style in 2005. (nl)

Case in point (3) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in grey, the rim of your pore is highlighted in purple, along with a 3D rendering from the movement in the DNA rod is exhibited.

MATLAB codes for data processing can be obtained at . Julia codes utilized for numerical simulation are available at .

Atomic power microscopy demonstrates that vaccinia topoisomerase IB generates filaments on DNA inside of a cooperative style

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There was 1 difficulty however — we didn't observe any measurable electrical conduction from The only polymer molecules. We concluded that at The only-molecule degree, conducting polymers have been in fact not these terrific conductors, which was rather disappointing. We cees dekker Hence broadened our check out to try to discover far more promising molecules.

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Cees Dekker is Distinguished University Professor at TU Delft. Trained as being a physicist, he pioneered nanotechnology with numerous discoveries on carbon nanotubes within the 1990s. Because 2000, he moved to single-molecule biophysics and nanobiology. His current research concentrates on (i) nanopores for protein sequencing; (ii) chromosome composition, specifically SMC motor protein; and (iii) creating a residing synthetic mobile from lifeless molecules. Dekker can be an elected member of your KNAW and fellow to your APS plus the IOP.

Developments in nanotechnology within the 1990s produced creating electronic gadgets from single molecules a chance. Cees Dekker recounts how his group produced a space-temperature transistor depending on just one carbon nanotube.

2004, discovery of latest physics in translocation of DNA through nanopores; initially experimental examine of ions conduction in nanofluidic channels; first electrochemistry with unique solitary-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; 1st electrical docking of microtubules on kinesin-coated nanostructures; initial biophysics characterization of your mechanical Homes of double-stranded RNA; and initial solitary-molecule study of DNA translocation by a restriction-modification enzyme.